Abstract of published research articles in Ayurveda
AYU Vol. 30 Issue No. 2 (April-June 2009)
Id.No.30204
An approach of Ashwagandha + Guggulu
inAtheromatousCHD associated with
Obesity
*
RaakheeMehra **MahadeoPrasad
***
G. S. Lavekar
Central Research
Institute for
Ayurveda, CCRAS, Dept. of AYUSH, Ministry of Health & F.W., Govt
of India, New Delhi.
Abstract:The Coronary Artery Disease or Coronary
Heart Disease is the single biggest killer (60%) and the most
common cause of maximum morbidity, ironically. Infact this is a
disease whose control is most in our hands and it is most life
style dependent. In accordance with the latest reports more than
13.7% of the adult population is suffering from coronary heart
disease in India, and this figure is constantly on the rise year
after year. The main cause of the disease is obesity in terms of
enhanced circumference, deposition of cholesterol and fat in the
inner smooth lining of the coronary arteries supplying blood to
the heart resulting in their blockages and obstruction to blood
flow through them. Atheromatous plaque is formed which
constricts the flow of blood, oxygen, and nutrients to the heart
muscles. With significant blockages, about 60% to 70% of the
vessel wall and exertion the increased demand of blood by the
heart is not met. More than 100 number of risk factors
responsible for the development of CHD are documented. Williams
in 1981 identified 246 risk factors that directly or indirectly
lead to the development and onset of heart disease. The excess
risk is closely related to the plasma concentration of LDLcholesterol and is inversely related to the plasma
concentration of LDL cholesterol and is inversely related to the
plasma HDL
Cholesterol concentration. There is also a weak correlation
between plasma triglyceride concentration and the incidence of
coronary artery disease. Moreover, numerous clinical trials have
shown that lowering high cholesterol concentrations by diet or
drugs can reduce the risk of cardiac events. Moreover, many
allopathic antihypertensive drugs have been shown to reduce
coronary mortality but by less than might have been anticipated,
possibly because many of these agents have potentially adverse
effects on lipid and glucose metabolism. Ayurvediya care from
both the preventive and therapeutic ways like primary protection
in terms of Swasthya Vritta with Aushadha
along with Pathyapathya and Ashwagandha+Guggulu
provide tremendous results with secondary cardio protectionby their anti
hyperlipidamic, antiatherosclerotic, antihypertensive actions.
All the patients
already on prescribed allopathic medicine and cardiac diet were
taken. An attempt to evaluate the efficacy of ayurvediya
Ashwagandha+Shuddha guggulu in 500mg twice daily in 20
patients of atheromatous coronary hypertensive heart patients
associated with obesity is made at Clinical Research Unit,
Safadarjang Hospital New Delhi during 2007.
