Abstract of published research articles in Ayurveda
AYU Vol. 30 Issue No. 3 (July-Sept. 2009)
Id.No.30310
Vacha (Acorus calamus) as an Ayurvedic Premedicant
*
D. N. Pande **
S.K. Mishra
Institute of Medical Sciences, BanarasHinduUniversity, Varanasi
Abstract:
Previously many indigenous herbal drugs mentioned in Ayurvedic
literature were experimentally screened on the animals and were
also studied clinically on the patients as pre-anesthetic
medication drug such as Brahmi, Sankhapushpi, Mandukparni,
Jatamansi etc. Modern research workers had also proved their
usefulness in the treatment of nervous and mental diseases. In
the same chain of research work, Vacha was selected for this
study and was used in the form of Ghanasatva. The clinical trial
was carried on 40 healthy patients. The patients were divided
into two groups randomly. The control and trial groups included
20 patients each of narrow age and weight distribution. The
patients of group I (Control) werepremedicated with Inj. Glycopyrrolate 0.2 mg IM and Tab.
Phenergan 50 mg orally with one ounce of plain water.The patients of group II (Trial) were premedicated with
Inj. Glycopyrrolate 0.2 mg I.M. and Vacha (Ghansatva) orally in
recommended doses with one ounce of plain water 90 minutes prior
to induction of anaesthesia. A standard anesthetic technique
with pre oxygenation for 3 minutes & Nitrous oxide with Ether
inhalation by spontaneous ventilation with Maggill’s open
circuit (Boyle’s apparatus) was used.The following parameters were used to see the efficacy of
the drug : Psychophysical effect before induction of
anaesthesia, Cardio-respiratory and other reflex response during
the course of subsequent anaesthesia & Post operative sickness
in immediate post operative period up to two hours.On the basis of observations, it was concluded that Vacha
controls the raised body temperature, produces good sedation and
it may be helpful in the patients with preexisting hyperthermia.It does not produce any C.V.S. & Respiratory depression.
Key words:
Medhya, Phenergan, Glycopyrrolate , sedation, apprehension and
induction
